Written by Zara Chechi Updated on 11 July 2018 The 100 most profitable companies on the Fortune Global 500 list generated between £34.8 billion ($45.7 billion) and £3.6 billion ($4.8 billion) in the last financial year (2016-2017). These are numbers that are too large to even comprehend. But when we divided profits by number of employees to determine who effectively has the most ‘profitable’ employees, the numbers were truly impressive:RankingCompany NameCountryProfit per Employee ($)Profit per Employee (£)1Fannie MaeUS1,759,0001,342,7592Gilead SciencesUS1,500,1111,145,1323Freddie MacUS1,306,419997,2754FacebookUS599,307457,4915AmgenUS402,187307,0166AppleUS393,853300,6547AlphabetUS270,329206,3608Taiwan Semiconductor ManufacturingTaiwan218,951167,1409Goldman Sachs GroupUS215,058164,16810AbbVieUS198,433151,47711SoftBank GroupJapan192,442146,90312QualcommUS187,049142,78713Tencent HoldingsChina159,533121,78214Westpac BankingAustralia155,244118,50815Shanghai Pudong Development BankChina151,287115,48716Commonwealth Bank of AustraliaAustralia148,749113,55017MicrosoftUS147,351112,48318Cisco SystemsUS145,712111,23219Industrial BankChina144,141110,032What the Tech is Going On?Many would expect the employees of tech companies such as Facebook, Apple and Google to be among the most profitable, but their employees ranked only 4th, 6th and 7th respectively. Surprisingly, those holding the top three spots were companies from traditional industries; mortgage providers and pharmaceuticals.A Productivity Party in the USAOf the top 10 companies in terms of profit per employee, eight are American. This is no surprise considering that the USA has the 6th most productive workforce in the world, and the biggest economy at £14.5 trillion ($19.4 trillion)Employees of the American Federal National Mortgage Association (FNMA), more commonly known as Fannie Mae, were the most profitable of all, effectively generating a staggering £1,342,759 ($1,759,000) each in profit last year.Profitable Employees: There’s a Science to itThe pharmaceutical industry is one of the most valuable in the US, with Americans having spent a staggering $450 billion on medicines last year alone. One of the most successful pharmaceutical companies is Gilead Sciences, who reported a profit of £10.3 billion ($13.5 billion) last year. This works out at an impressive £1.1 million ($1.5 million) in profit per employee.Gilead are famous for their pioneering treatments of both HIV and Hepatitis C, although the high cost of drugs for the latter has caused a lot of controversy in recent months. Levels of Hep C in the US are currently at a 15 year high, and the high cost of the drug (£56,000, or $74,760, per course) has led insurance companies to impose strict criteria on who can qualify to receive it through their insurance.What Next?Fannie Mae employees may hold the top spot by some margin this year, but with a whole new generation of disruptive fintech startups threatening the traditional mortgage industry, we have to wonder if the leaderboard won’t look quite different in years to come. Zara Chechi Zara is a law grad with a penchant for wordsmithing. As Expert Market’s CRM and payroll expert, she relishes researching and writing expert content.